SCOR: Structural Classification of RNA, version 2.0

SCOR: Structural Classification of RNA, version 2.0
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DOI:
10.1093/nar/gkh080
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发表时间:
2004-01-01
影响因子:
14.9
通讯作者:
Holbrook, SR
Holbrook, SR
中科院分区:
生物学2区
文献类型:
--
作者:
Tamura, M;Hendrix, DK;Holbrook, SR

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SCOR,RNA的结构分类(scor.lbl.gov),是一个数据库,旨在提供一个全面的角度和理解RNA基序的三维结构,功能,三级相互作用和它们之间的关系。SCOR 2.0是一个重大的扩展,并引入了一个新的分类组织。新版本将分类表示为有向无环图(DAG),它允许分类节点具有多个父节点,与SCOR 1.2中使用的严格分层分类相反。SCOR 2.0在更新后的搜索引擎中支持三种类型的查询词:PDB或NDB标识符、核苷酸序列和关键字。我们还为所有信息提供可解析的XML文件。这个新版本包含了截至2003年5月15日PDB中的511个RNA条目。共有5880个二级结构元件被分类:2104个发夹环和3776个内环。文献中报道的RNA基序,如“扭结”和“GNRA环”,现在与定义和描述沿着被纳入结构分类。
SCOR, the Structural Classification of RNA (http:// scor.lbl.gov), is a database designed to provide a comprehensive perspective and understanding of RNA motif three-dimensional structure, function, tertiary interactions and their relationships. SCOR 2.0 represents a major expansion and introduces a new classification organization. The new version represents the classification as a Directed Acyclic Graph (DAG), which allows a classification node to have multiple parents, in contrast to the strictly hierarchical classification used in SCOR 1.2. SCOR 2.0 supports three types of query terms in the updated search engine: PDB or NDB identifier, nucleotide sequence and keyword. We also provide parseable XML files for all information. This new release contains 511 RNA entries from the PDB as of 15 May 2003. A total of 5880 secondary structural elements are classified: 2104 hairpin loops and 3776 internal loops. RNA motifs reported in the literature, such as 'Kink turn' and 'GNRA loops', are now incorporated into the structural classification along with definitions and descriptions.