DIGITAL COMPUTER PROCEDURE FOR CONVERSION OF PCO2 INTO BLOOD CO2 CONTENT

DIGITAL COMPUTER PROCEDURE FOR CONVERSION OF PCO2 INTO BLOOD CO2 CONTENT
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DOI:
10.1016/0034-5687(67)90028-x
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发表时间:
1967-01-01
期刊:
RESPIRATION PHYSIOLOGY
影响因子:
--
通讯作者:
KELMAN, GR
KELMAN, GR
中科院分区:
其他
文献类型:
--
作者:
KELMAN, GR

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本文描述了一种在不同温度下和在存在代谢性酸中毒或酸中毒的情况下将CO2张力转换为全血CO2含量的数字计算机程序。根据Henderson-Has-selbalch方程(考虑血浆中pK和CO2溶解度对温度和pH值的依赖性)计算血浆的CO2含量;然后根据货车Slyke和Sendroy的实验数据,使用[CO2]细胞[CO2]血浆比率的经验近似值测定血液的CO2含量。这个计算机程序是独立的,可以不加修改地编入更大的程序中。
A digital computer procedure for the conversion of CO2 tension into whole blood CO2 content at various temperatures and in the presence of metabolic acidosis or alkalosis is described. The CO2 content of the plasma is calculated from the Henderson-Has-selbalch equation (allowing for the dependence of pK and CO2 solubility in plasma on temperature and pH); and the CO2 content of the blood is then determined using an empirical approximation of the ratio [CO2] cells [CO2] plasma based on the experimental data of Van Slyke and Sendroy. This computer procedure is self-contained and is ready for inclusion in larger programs without modification.