The multifaceted impact of anxiety and depression on patients with rheumatoid arthritis
The multifaceted impact of anxiety and depression on patients with rheumatoid arthritis
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DOI：
10.1186/s41927-019-0092-5
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发表时间：
2019-01-01
期刊：
影响因子：
2.2
通讯作者：
Li, Nan
中科院分区：
文献类型：
--
作者：
Peterson, Steve;Piercy, James;Li, Nan
背景资料：类风湿关节炎（RA）患者的情绪障碍（如焦虑和抑郁）的患病率高于一般人群。鉴于这种关联，本研究的主要目的是评估焦虑或抑郁对美国（USA）和欧洲RA患者的增量影响，与基础RA疾病的影响无关。研究方法：来自美国和5个欧洲国家的风湿病学家（n=408）完成了研究期间连续咨询的预定数量RA患者的患者记录表;这些患者完成了患者报告的问卷。采用描述性统计和多元回归分析方法，探讨类风湿关节炎患者焦虑、抑郁情绪与治疗和经济结局的关系。结果如下：在完成所有相关问卷部分的1015名医生和患者对中，390名（38.4%）患者自我报告焦虑或抑郁，而180名（17.7%）患者的医生报告有焦虑或抑郁。控制年龄、性别、体重指数和临床因素（发作和严重程度）后，多元回归分析表明，焦虑或抑郁患者更常经历治疗不满（比值比[OR] 2.28; P
Background: The prevalence of mood disturbances such as anxiety and depression is greater in rheumatoid arthritis (RA) patients than in the general population. Given this association, the primary aim of this study was to assess the incremental impact of anxiety or depression on patients with RA from the United States of America (USA) and Europe, independent of the impact of the underlying RA disease. Methods: Rheumatologists (n=408) from the USA and 5 European countries completed patient record forms for a predetermined number of RA patients who consulted consecutively during the study period; these patients completed patient-reported questionnaires. Descriptive statistics and multivariate regression were used to investigate the relationship between anxiety and depression with treatment and economic outcomes in RA patients. Results: Of 1015 physician and patient pairs who completed all relevant questionnaire sections, 390 (38.4%) patients self-reported anxiety or depression, while 180 (17.7%) patients were reported to have anxiety or depression by their physicians. Controlling for age, gender, body mass index and clinical factors (flaring and severity), multiple regression analyses suggested that patients with anxiety or depression more often experienced treatment dissatisfaction (odds ratio [OR] 2.28; P