Racial and ethnic differences in the seroprevalence of 6 infectious diseases in the United States: Data from NHANES III, 1988-1994
Racial and ethnic differences in the seroprevalence of 6 infectious diseases in the United States: Data from NHANES III, 1988-1994
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DOI：
10.2105/ajph.94.11.1952
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发表时间：
2004-11-01
影响因子：
12.7
通讯作者：
Kington, RS
中科院分区：
文献类型：
--
作者：
McQuillan, GM;Kruszon-Moran, D;Kington, RS
目标。在根据风险类别分层的分析中，我们检查了选定的感染源的血清阳性率的种族/民族差异，以确定模式，并确定人口统计学、社会经济和行为特征是否解释了这些差异。对第三次全国健康与营养普查资料进行分析，比较甲、乙、丙型肝炎病毒、弓形虫、幽门螺杆菌、单纯疱疹病毒2型感染情况。在低风险类别的人中，种族/民族差异更大。在大多数感染性病原体的情况下，与种族/民族相关的风险在这一类别中几乎是高危类别中的两倍。对社会经济因素的分层和调整减少或消除了高风险但不是低风险群体中感染流行率的种族/族裔差异，其中种族/族裔仍然很重要，可能是未测量的风险因素的替代品。
Objectives. We examined racial/ethnic differences in the seroprevalence of selected infectious agents in analyses stratified according to risk categories to identify patterns and to determine whether demographic, socioeconomic, and behavioral characteristics explain these differences.Methods. We analyzed data from the third National Health and Nutrition Examination Survey, comparing differences among groups in regard to the prevalence of infection with hepatitis A, B, and C viruses, Toxoplasma gondii, Helicobacter pylori, and herpes simplex virus type 2.Results. Racial/ethnic differences were greater among those in the low-risk category. In the case of most infectious agents, odds associated with race/ethnicity were almost 2 times greater in that category than in the high-risk category.Conclusions. Stratification and adjustment for socioeconomic factors reduced or eliminated racial/ethnic differences in the prevalence of infection in the high-risk but not the low-risk group, wherein race/ethnicity remained significant and might have been a surrogate for unmeasured risk factors.