Yellow fever vaccination in non-immunocompetent patients
Yellow fever vaccination in non-immunocompetent patients
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DOI：
10.1016/j.medmal.2008.06.031
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发表时间：
2008-10-01
影响因子：
5
通讯作者：
Malvy, D.
中科院分区：
文献类型：
--
作者：
Bruyand, M.;Receveur, M. -C.;Malvy, D.
任何在黄热病 (YF) 流行的国家旅行且没有黄热病疫苗接种禁忌症的人都可以接种疫苗。这种疫苗接种很少会诱发潜在致命的神经性或内脏性疾病。对于严重免疫缺陷的患者，禁止接种疫苗，因为由于疫苗株的致病性，接种疫苗后可能会发生疫苗后脑炎。由于 60 岁及以上人群患内脏疾病的风险增加，因此在接种疫苗前评估老年人的总体健康状况非常重要。孕妇不应接种疫苗，除非不可避免地前往流行区。六个月以下的新生儿禁止接种 YF 疫苗。实或筏，先天性免疫缺陷。白血病、淋巴瘤、癌症和免疫抑制治疗是该疫苗接种的禁忌症。尽管如此，在骨髓移植后和两年内没有移植物抗宿主病或免疫抑制治疗的情况下，YF 免疫是可能的。没有数据支持捐赠者在移植前进行免疫接种可以为接受者提供预防黄热病的保护。低剂量。短期皮质类固醇疗程，无论是全身治疗还是关节内注射，都不是 YF 疫苗接种的禁忌症。临床状态稳定且 T CD4 细胞计数高于每毫米立方体 200 个细胞的 HIV 感染患者可以接种疫苗。胸腺疾病，包括胸腺瘤和胸腺切除术，是 YF 疫苗接种的禁忌症。最后，在最近一次疫苗接种后 10 年内，抗体的残留水平仍然很高，可以提供保护，从而在出现问题时避免重新接种疫苗。 (C) 2008 Elsevier Masson SAS。吨外汇储备。
Any person travelling in countries where yellow fever (YF) is endemic and without presenting contra-indication for the vaccination against YF May be vaccinated. This vaccination can very rarely induce a potentially lethal neurotropic or viscerotropic disease. In severely immunodeficient patients, the vaccination is contra-indicated because postvaccinal encephalitis may occur after the vaccination, due to vaccine strain pathogenecity. It is important to evaluate the general health status in elderly individuals before vaccinating because of the increased risk of viscerotropic disease in people of 60 years of age and over. Pregnant women should not be vaccinated, except if departure to an endemic zone is unavoidable. YF vaccination is contra-indicated for newborns under six months of a e. Solid or-an,rafts, congenital immunodeficiency. leukemia, lymphoma, cancer, and immunosuppressive treatments are contra-indications for this vaccination. Nevertheless, YF immunization is possible after a bone marrow graft and a two-year period without graft-versus-host disease or immunosuppressive treatment. There is no data to Support that immunization of the donor prior to the graft Could confer protection against yellow Fever to the recipient. Low doses. short Courses of corticosteroids either as systemic treatment or intra-articular injections are not contra-indications for YF vaccination. Patients infected with HIV with stable clinical Status and T CD4-cell count above 200 cells per millimetre cube may lie vaccinated. Thymic diseases, including thymoma and thymectomy, are contra-indications for YF vaccination. Finally, it substantial residual level of antibodies beyond 10 years after the latest vaccination Could confer protection, thus avoiding a new vaccination when it is an issue. (C) 2008 Elsevier Masson SAS. Tons droits reserves.