Enrichment of specific suppressor T cells and characterization of their surface markers.
Enrichment of specific suppressor T cells and characterization of their surface markers.
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富集特定的抑制剂T细胞及其表面标记的表征。
DOI：
10.1084/jem.146.5.1450
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发表时间：
1977-11-01
期刊：
影响因子：
--
通讯作者：
Miller JF
中科院分区：
文献类型：
--
作者：
Taniguchi M;Miller JF
描述了一种简单的方法，其允许抗原特异性抑制性T细胞富集超过100倍。富集的细胞具有以下特征性标志物：IG-、Thy-1+、Ly-1-、Ly-2，3+和I-J+。在补体存在下，I-J亚区基因产物特异性抗血清可直接杀死30%以上的该群体。
A simple method is described which allows antigen-specific suppressor T cells to be enriched by greater than 100-fold. The enriched cells have the following characteristic markers: Ig-, Thy-1+, Ly-1-, Ly-2,3+, and I-J+. More than 30% of this population could be killed directly by an antiserum specific for the I-J subregion gene product in the presence of complement.