DIAMETERS OF RETINAL BLOOD VESSELS IN A HEALTHY COHORT AS MEASURED BY SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY

DIAMETERS OF RETINAL BLOOD VESSELS IN A HEALTHY COHORT AS MEASURED BY SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY
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DOI:
10.1097/iae.0b013e31829477f2
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发表时间:
2013-10-01
影响因子:
3.3
通讯作者:
Goldstein, Michaella
Goldstein, Michaella
中科院分区:
医学2区
文献类型:
--
作者:
Goldenberg, Dafna;Shahar, Jonathan;Goldstein, Michaella

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目的:描述一种利用光谱域光学相干断层扫描测量视网膜大血管直径的方法。方法:对29例(58只眼)接受光谱域光学相干断层扫描的健康受试者进行前瞻性队列研究。在视盘的上下边界放置两个立方体的水平扫描,以包括大的颞叶视网膜血管。在10个测量点(距视盘边缘上下480~1440 mm)测量血管直径,计算动静脉比。结果:研究对象平均年龄为41.45±15.53岁。患者没有眼部或全身病理改变。视网膜动脉直径为135.73±15.64 mm,静脉直径为151.32±15.22 mm,1440 mm时分别为123.01±13.43 mm和137.69±13.84 mm。所有测量点的动静脉比均为+/-0.9。结论:这是一种利用光谱域光学相干断层成像技术无创测量视网膜血管直径的新方法。这种方法可能有助于评估视网膜和系统性血管疾病。
Purpose: To describe a method for measuring the diameters of large retinal blood vessels by means of spectral domain optical coherence tomography.Methods: Prospective cohort study of 29 healthy subjects (58 eyes) who underwent a spectral domain optical coherence tomography examination. Two cubes of horizontal scans were placed at the superior and inferior borders of the disk to include the large temporal retinal vessels. Vessels diameters were measured, and an artery-to-vein ratio was calculated at 10 measurement points (480-1440 mm superiorly and inferiorly from the optic disk border).Results: The mean age of the study subjects was 41.45 +/- 15.53 years. Patients had no ocular or systemic pathologies. The mean diameter of the retinal artery was 135.73 +/- 15.64 mm and of the vein 151.32 +/- 15.22 mm at the measurement point of 480 mm, with a gradual decrease to 123.01 +/- 13.43 mm and 137.69 +/- 13.84 mm, respectively, at 1440 mm. The artery-to-vein ratio was +/- 0.9 at all points of measurement.Conclusion: This is a new noninvasive method for retinal blood vessels diameter measurement using the spectral domain optical coherence tomography imaging modality. This method may aid in evaluation of retinal and systemic vascular diseases.