Diffuse axonal injury: detection of changes in anisotropy of water diffusion diffusion-weighted imaging
Diffuse axonal injury: detection of changes in anisotropy of water diffusion diffusion-weighted imaging
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DOI：
10.1007/s00234-002-0891-y
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发表时间：
2003-01-01
期刊：
影响因子：
2.8
通讯作者：
Fung, KKL
中科院分区：
文献类型：
--
作者：
Chan, JHM;Tsui, EYK;Fung, KKL
白色物质的有髓鞘轴突在水扩散方面表现出明显的方向差异。我们对10例颅脑损伤患者进行了弥散加权成像，以探讨利用水弥散各向异性定量弥漫性轴索损伤的可行性。我们发现在T2和T2* 加权像上有或没有信号异常的区域，弥散各向异性指数显著降低。我们的结论是水扩散各向异性敏感指数的一个潜在的有用的，和定量的诊断和评估患者的弥漫性轴索损伤的方法。
Myelinated axons of white matter demonstrate prominent directional differences in water diffusion. We performed diffusion-weighted imaging on ten patients with head injury to explore the feasibility of using water diffusion anisotropy for quantitating diffuse axonal injury. We showed significant decrease in diffusion anisotropy indices in areas with or without signal abnormality on T2 and T2*-weighted images. We conclude that the water diffusion anisotropy sensitive index a potentially useful, and quantitative way of diagnosing and assessing patients with diffuse axonal injury.