Research Landscape on Atherosclerotic Cardiovascular Disease and Inflammation: A Bibliometric and Visualized Study
Research Landscape on Atherosclerotic Cardiovascular Disease and Inflammation: A Bibliometric and Visualized Study
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动脉粥样硬化性心血管疾病和炎症的研究概况：文献计量和可视化研究
DOI：
10.31083/j.rcm2309317
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发表时间：
2022-09
影响因子：
2.7
通讯作者：
Hao Xu
中科院分区：
文献类型：
--
作者：
Wende Tian;Tai Zhang;Xinyi Wang;Jie Zhang;Jianqing Ju;Hao Xu
背景：动脉粥样硬化性心血管疾病（ASCVD）是世界范围内的主要杀手和卫生保健负担。动脉粥样硬化是常见的病理基础，在过去的几年里一直与炎症有关。也出现了一些有希望的结果，表明靶向炎症作为减少心血管事件的潜在治疗选择的作用。鉴于炎症在ASCVD中的致病作用，我们建议使用文献计量学分析来评估ASCVD和炎症的全球研究架构。研究方法：对Clarivate Analytics的Web of Science Core Collection进行了检索，以查找2012年至2022年期间发表的该领域的文章。每年的出版物数量已经通过GraphPad Prism可视化。CiteSpace和VOSviewer用于生成有关国家，机构和作者合作的知识地图，并表示ASCVD和炎症研究的景观以及揭示当前的焦点。结果：本研究共检查了19，053篇出版物。来自中国的出版物最多（6232，32.71%）。首都医科大学是生产率最高的机构（410，2.15%）。克里斯蒂安·韦伯发表的文章最多（75篇，0.39%）。PLoS one被认为是最多产的期刊（706，3.71%）。《循环》是被共引最多的期刊（13276，2.81%）。关键词与正在进行的强引用爆发是“核苷酸结合寡聚化（NOD），富含亮氨酸重复序列（LRR）的蛋白质（NLRP 3）炎性体”，“肠道菌群”，“外泌体”，“lncRNA”等结论：它可以表明ASCVD和炎症研究受益于手稿，有很高的影响力，在科学界。亚洲、欧洲和北美国家在数量、质量和合作参数方面占主导地位。NLRP 3炎性体、肠道微生物群和三甲胺N-氧化物、自噬、lncRNA、外泌体和核因子红细胞2相关因子2被描述为该领域的热门主题。
Background: The atherosclerotic cardiovascular disease (ASCVD) is a major killer and health care burden worldwide. Atherosclerosis, the common pathological foundation, has been associated with inflammation over the past few years. Some promising results also have emerged suggesting the role of targeting inflammation as a potential therapeutic option to reduce cardiovascular events. In light of the pathogenic role that inflammation plays in ASCVD, we propose to evaluate the worldwide research architecture for ASCVD and inflammation using bibliometric analysis. Methods: A search of the Web of Science Core Collection of Clarivate Analytics was performed for articles in the field published between 2012 and 2022. The number of publications per year has been visualized using GraphPad Prism through time. CiteSpace and VOSviewer were used to generate knowledge maps about the collaboration of countries, institutions, and authors, and to represent the landscape on ASCVD and inflammation research as well as to reveal current foci. Results: There were a total of 19,053 publications examined in this study. The most publications came from China (6232, 32.71%). Capital Med Univ was the most productive institution (410, 2.15%). Christian Weber published the greatest number of articles (75, 0.39%). PloS one was identified as the most prolific journal (706, 3.71%). Circulation was the most co-cited journal (13276, 2.81%). Keywords with the ongoing strong citation bursts were “nucleotide-binding oligomerization (NOD), Leucine-rich repeat (LRR)-containing protein (NLRP3) inflammasome”, “intestinal microbiota”, “exosome”, “lncRNAs”, etc. Conclusions: It can be shown that ASCVD and inflammation research benefited from manuscripts that had a high impact on the scientific community. Asian, European and North American countries dominated in the field in terms of quantitative, qualitative and collaborative parameters. The NLRP3 inflammasome, gut microbiota and trimethylamine N-oxide, autophagy, lncRNAs, exosomes, and nuclear factor erythroid 2-related factor 2 were described to be hot themes in the field.