Geomagnetic Storms Can Trigger Stroke Evidence From 6 Large Population-Based Studies in Europe and Australasia

Geomagnetic Storms Can Trigger Stroke Evidence From 6 Large Population-Based Studies in Europe and Australasia
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DOI:
10.1161/strokeaha.113.004577
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发表时间:
2014-06-01
期刊:
影响因子:
8.3
通讯作者:
Kasabov, Nikola
Kasabov, Nikola
中科院分区:
医学1区
文献类型:
--
作者:
Feigin, Valery L.;Parmar, Priya G.;Kasabov, Nikola

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背景与目的:虽然将心血管疾病与地磁活动联系起来的研究正在积累,但地磁活动对卒中发生的影响的有力证据有限且存在争议。方法:我们采用时间分层的病例交叉研究设计,分析了1981年至2004年间在新西兰、澳大利亚、英国、法国和瑞典进行的几项大型人群卒中发病率研究(在16031764人年的观察中收集了11453例卒中患者的信息)中个体参与者和每日地磁活动(由Ap指数测量)的数据。计算风险比和相应的95%置信区间(ci)。结果:总体而言,地磁风暴(Ap指数60+)与卒中发生风险增加19%相关(95% CI, 11%-27%)。地磁风暴的触发效应在所有卒中合并组中最为明显,年龄在50%的人群中:中度地磁风暴(60-99 Ap指数)与卒中发生风险增加27% (95% CI, 8%-48%)相关,强地磁风暴(100-149 Ap指数)与卒中发生风险增加52% (95% CI, 19%-92%)相关,严重/极端地磁风暴(Ap指数150+)与卒中发生风险增加52% (95% CI, 19%-94%)相关(趋势检验,P
Background and Purpose-Although the research linking cardiovascular disorders to geomagnetic activity is accumulating, robust evidence for the impact of geomagnetic activity on stroke occurrence is limited and controversial.Methods-We used a time-stratified case-crossover study design to analyze individual participant and daily geomagnetic activity (as measured by Ap Index) data from several large population-based stroke incidence studies (with information on 11 453 patients with stroke collected during 16 031 764 person-years of observation) in New Zealand, Australia, United Kingdom, France, and Sweden conducted between 1981 and 2004. Hazard ratios and corresponding 95% confidence intervals (CIs) were calculated.Results-Overall, geomagnetic storms (Ap Index 60+) were associated with 19% increase in the risk of stroke occurrence (95% CI, 11%-27%). The triggering effect of geomagnetic storms was most evident across the combined group of all strokes in those aged 50%: moderate geomagnetic storms (60-99 Ap Index) were associated with a 27% (95% CI, 8%-48%) increased risk of stroke occurrence, strong geomagnetic storms (100-149 Ap Index) with a 52% (95% CI, 19%-92%) increased risk, and severe/extreme geomagnetic storms (Ap Index 150+) with a 52% (95% CI, 19%-94%) increased risk (test for trend, P