Sympathetic influences on cardiac rate and contractility during acute stress in humans.
Sympathetic influences on cardiac rate and contractility during acute stress in humans.
复制标题
人类急性应激期间交感神经对心率和收缩力的影响。
DOI：
10.1111/j.1469-8986.1974.tb00566.x
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发表时间：
1974
期刊：
影响因子：
3.7
通讯作者：
John Manning
中科院分区：
文献类型：
--
作者：
P. Obrist;James E. Lawler;James L. Howard;Kenneth W. Smithson;Philip L. Martin;John Manning
据报道，有一些实验涉及评估交感神经对正常年轻人在压力反应时间任务中心率和心肌收缩力的影响。在准备期间，只能发现迷走神经对心率变化的影响，这与伴随的躯体活动有关。在预期电击以及此后更持续的一段时间内，交感神经的影响对心率和收缩力都表现出来，而这与伴随的躯体活动无关。在后续研究中，评估了直接从桡动脉测量的血压与收缩力和心率之间的关系。尽管有时发现心率和收缩力大幅增加后血压会出现明显的阶段性下降，但并未发现交感神经对心脏的影响继发于降压作用。数据表明，交感神经对心脏的影响通常非常小，但当机体试图应对压力时，交感神经会由强烈的压力引起。
Experiments are reported concerning an evaluation of sympathetic influences on heart rate and cardiac contractility in normal young adult humans during a stressful reaction time task. During the preparatory interval only vagal influences on heart rate change could be found which were related to concomitant somatic activity. In expectation of the shock and for a more sustained period thereafter, sympathetic influences became manifested on both heart rate and contractility which were independent of concomitant somatic activity. In a follow-up study, the relationship was evaluated between blood pressure, as measured directly from the radial artery, and both contractility and heart rate. Sympathetic influences on the heart were not found to be secondary to depressor effects, although appreciable phasic decreases in blood pressure were sometimes found to follow the onset of large increases in heart rate and contractility. The data suggest that sympathetic influences on the heart are normally very minimal but are evoked by intense stress when the organism attempts to cope with the stress.