Room temperature dehalogenation of chloroarenes by polymethylhydrosiloxane (PMHS) under palladium catalysis
Room temperature dehalogenation of chloroarenes by polymethylhydrosiloxane (PMHS) under palladium catalysis
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DOI：
10.1016/s0040-4039(02)02212-8
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发表时间：
2002-12-02
影响因子：
1.8
通讯作者：
Maleczka, RE
中科院分区：
文献类型：
--
作者：
Rahaim, RJ;Maleczka, RE
报道了第一种用聚甲基二硅氧烷(PMHS)还原氯代芳烃的方法。催化量的醋酸钯(II)与PMHS和KF水溶液在室温下可快速加氢脱卤化芳香氯化合物。该方法的温和表现在它对酮、酰胺、酯、腈、醚、硼酸酯和胺的耐受性。(C)2002爱思唯尔科学有限公司。保留所有权利。
The first method for the reduction of chloroarenes by polymethylhydiosiloxane (PMHS) is reported. Catalytic amounts of palladium(II) acetate in combination with PMHS and aqueous KF will rapidly hydrodehalogenate aryl chlorides at room temperature. The mildness of the method is demonstrated by its tolerance of ketones, amides, esters, nitriles, ethers, borate esters, and amines. (C) 2002 Elsevier Science Ltd. All rights reserved.