Biochemical properties of acteylcholine receptor subunits from Torpedo californica.
Biochemical properties of acteylcholine receptor subunits from Torpedo californica.
复制标题
加州鱼雷乙酰胆碱受体亚基的生化特性。
作者：
J. Lindstrom;J. Merlie;G. Yogeeswaran
来自Torpedo Californica的电气器官的四个多肽链通过十二烷基硫酸钠的制剂电泳纯化了来自Torpedo Californica的乙酰胆碱受体。他们的明显摩尔比α/beta/gamma/delta为2：1：1：1。这些链不容易通过氨基酸或碳水化合物组成区分，而是通过明显的分子量和多肽图来区分。通过肽图，在这些链之间或这些链中的任何一个和较高的分子量链之间在受体增强的膜片段中发现的较高的分子量链之间没有明显的同源性。
Four polypeptide chains composing acetylcholine receptors from the electric organ of Torpedo californica were purified by preparative electrophoresis in sodium dodecyl sulfate. Their apparent mole ratio alpha/beta/gamma/delta is 2:1:1:1. These chains are not readily distinguished by amino acid or carbohydrate composition but are distinguished by apparent molecular weight and polypeptide maps. By peptide maps, no extensive homology is evident between these chains or between any of these chains and higher molecular weight chains found in receptor-enriched membrane fragments.