PREVALENCE AND TYPES OF DEMENTIA IN THE VERY OLD - RESULTS FROM THE CANADIAN-STUDY-OF-HEALTH-AND-AGING
PREVALENCE AND TYPES OF DEMENTIA IN THE VERY OLD - RESULTS FROM THE CANADIAN-STUDY-OF-HEALTH-AND-AGING
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DOI：
10.1212/wnl.44.9.1593
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发表时间：
1994-09-01
期刊：
影响因子：
9.9
通讯作者：
FUNG, TS
中科院分区：
文献类型：
--
作者：
EBLY, EM;PARHAD, IM;FUNG, TS
我们报告了85岁及以上的加拿大人患痴呆症的情况。本研究的目的是确定老年痴呆症的患病率是否继续增加，并确定痴呆的类型及其在该年龄组中的相对比例。我们收集的数据是加拿大健康与老龄化研究（1990年至1992年）的一部分，该研究包括来自283,510名居住在社区或机构的85岁及以上的加拿大人的1,835名受试者样本。85岁及以上人群的痴呆患病率为28.5%，是75- 84岁人群的两倍多。在85岁至89岁的样本（n= 1332）中，痴呆的患病率为23%，在90岁至94岁的样本（n=371）中，痴呆的患病率增加到40%，在95岁及以上的样本（n=104）中，痴呆的患病率达到58%。总的来说，阿尔茨海默病（AD；可能或可能）占所有痴呆症的75%；仅血管性病因就占痴呆症的13%。65岁以后，临床诊断的AD病例占血管性痴呆病例的比例显著增加，85岁以上年龄组的比例高于较年轻年龄组（65 - 84岁）。
We report on the prevalence of dementia in Canadians age 85 years and older. The purpose of this study was to determine whether the prevalence of dementia continued to increase in the very old, and to define the types of dementia and their relative proportions in this age group. We collected data as part of the Canadian Study of Health and Aging (1990 to 1992), which consisted of a sample of 1,835 subjects from a population of 283,510 Canadians who were 85 years of age and older residing in the community or in institutions. The prevalence of dementia in the 85 years and older group was 28.5%, more than twice that of the 75- to 84-years cohort. The prevalence of dementia of 23% in the 85- to 89-years sample (n=1,332) increased to 40% in the 90 to 94 years group (n=371) and, in the 95 years and older sample (n=104), reached 58%. Overall, Alzheimer's disease (AD; probable or possible) accounted for 75% of all, dementias; a vascular etiology alone accounted for 13% of dementias. The proportion of clinically diagnosed AD cases to vascular dementia cases increased significantly after age 65 and was higher in the 85+ group than in a younger cohort (65 to 84 years).