Hepatic Steatosis (Fatty Liver Disease) in Asymptomatic Adults Identified by Unenhanced Low-Dose CT
Hepatic Steatosis (Fatty Liver Disease) in Asymptomatic Adults Identified by Unenhanced Low-Dose CT
复制标题
DOI：
10.2214/ajr.09.2590
复制
发表时间：
2010-03-01
影响因子：
5
通讯作者：
Hinshaw, J. Louis
中科院分区：
文献类型：
--
作者：
Boyce, Cody J.;Pickhardt, Perry J.;Hinshaw, J. Louis
OBJECTIVE.本研究的目的是调查一个无症状的美国人的脂肪肝患病率。S.成人人群使用非增强CT的衰减值作为参考标准。我们还评估了已知的临床危险因素对诊断的效用。对于3,357例连续无症状成人（1,865例女性和1,492例男性;平均年龄57.0岁），使用低剂量结肠造影技术通过非增强CT获得肝脏和脾脏CT衰减值（Hounsfield单位）进行结直肠癌筛查。应用脂肪变性的多种衰减标准，包括肝脏阈值和肝脏和脾脏衰减的比较。将相关临床风险因素与CT肝脏衰减进行比较
OBJECTIVE. The purpose of this study was to investigate the prevalence of hepatic steatosis in an asymptomatic U. S. adult population using attenuation values at unenhanced CT as the reference standard. We also assessed the utility of known clinical risk factors for diagnosis.MATERIALS AND METHODS. For 3,357 consecutive asymptomatic adults (1,865 women and 1,492 men; mean age, 57.0 years), hepatic and splenic CT attenuation values (Hounsfield units) were obtained by unenhanced CT using a low-dose colonography technique for colorectal cancer screening. Multiple attenuation criteria for steatosis were applied, including liver thresholds and comparison of liver and spleen attenuation. Relevant clinical risk factors were compared against a CT liver attenuation