The SCARECROW gene regulates an asymmetric cell division that is essential for generating the radial organization of the Arabidopsis root
The SCARECROW gene regulates an asymmetric cell division that is essential for generating the radial organization of the Arabidopsis root
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DOI：
10.1016/s0092-8674(00)80115-4
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发表时间：
1996-08-09
期刊：
影响因子：
64.5
通讯作者：
Benfey, PN
中科院分区：
文献类型：
--
作者：
DiLaurenzio, L;WysockaDiller, J;Benfey, PN
在拟南芥根分生组织中，起始细胞经历不对称分裂以产生根的细胞谱系。稻草人突变导致根缺少一个细胞层，这是由于通常产生皮层和内皮层的不对称分裂被破坏。组织特异性标记表明突变体中形成了异质细胞类型。SCARECROW（SCR）的氨基酸序列推测它是一个新的转录因子家族的成员。SCR在皮质/内胚层初始细胞和内胚层细胞谱系中表达。组织特异性表达在转录水平上受到调控。这些结果表明SCR在调节根的径向组织中起关键作用。
In the Arabidopsis root meristem, initial cells undergo asymmetric divisions to generate the cell lineages of the root. The scarecrow mutation results in roots that are missing one cell layer owing to the disruption of an asymmetric division that normally generates cortex and endodermis. Tissue-specific markers indicate that a heterogeneous cell type is formed in the mutant. The deduced amino acid sequence of SCARECROW (SCR) suggests that it is a member of a novel family of putative transcription factors. SCR is expressed in the cortex/endodermal initial cells and in the endodermal cell lineage. Tissue-specific expression is regulated at the transcriptional level. These results indicate a key role for SCR in regulating the radial organization of the root.