TIMS: TaqMan Information Management System, tools to organize data flow in a genotyping laboratory
TIMS: TaqMan Information Management System, tools to organize data flow in a genotyping laboratory
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DOI：
10.1186/1471-2105-6-246
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发表时间：
2005-10-12
影响因子：
3
通讯作者：
Canzian, F
中科院分区：
文献类型：
--
作者：
Monnier, S;Cox, DG;Canzian, F
背景：单核苷酸多态性（SNP）基因分型是生物医学研究中的主要活动。Taqman技术是最常用的方法之一。它产生大量难以手工处理的数据。实验室不配备实验室信息管理系统（LIMS）需要的工具来组织的数据flow.Results：我们提出了一个包的Visual Basic程序集中在样品管理和解析的输入和输出TaqMan文件。该代码是用Visual Basic编写的，嵌入在Microsoft Office软件包中，它允许任何人都可以访问这些工具，没有任何编程技能和基本的计算机requires.Conclusion：我们已经创建了有用的工具，专注于TaqMan基因分型数据的管理，在基因分型实验室whithout一个更复杂和昂贵的系统，如LIMS的一个关键问题。
Background: Single Nucleotide Polymorphism ( SNP) genotyping is a major activity in biomedical research. The Taqman technology is one of the most commonly used approaches. It produces large amounts of data that are difficult to process by hand. Laboratories not equipped with a Laboratory Information Management System ( LIMS) need tools to organize the data flow.Results: We propose a package of Visual Basic programs focused on sample management and on the parsing of input and output TaqMan files. The code is written in Visual Basic, embedded in the Microsoft Office package, and it allows anyone to have access to those tools, without any programming skills and with basic computer requirements.Conclusion: We have created useful tools focused on management of TaqMan genotyping data, a critical issue in genotyping laboratories whithout a more sophisticated and expensive system, such as a LIMS.