Preparation of 2,5-Bis(Aminomethyl)Furan by Direct Reductive Amination of 2,5-Diformylfuran over Nickel-Raney Catalysts
Preparation of 2,5-Bis(Aminomethyl)Furan by Direct Reductive Amination of 2,5-Diformylfuran over Nickel-Raney Catalysts
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DOI：
10.4236/gsc.2015.53015
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发表时间：
2015-07
期刊：
影响因子：
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通讯作者：
Ngoc-Thuc Le;Areum Byun;Yohan Han;Kee-In Lee;Hyungrok Kim
中科院分区：
文献类型：
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作者：
Ngoc-Thuc Le;Areum Byun;Yohan Han;Kee-In Lee;Hyungrok Kim
首次报道了在工业型镍-雷尼催化剂和酸处理镍-雷尼催化剂上，2，5-二甲酰基呋喃（DFF）与氨直接还原胺化制2，5-双（氨甲基）呋喃（BAF）。考察了反应介质、反应温度、氢气压力等因素对反应的影响。在THF-水混合反应介质中，酸处理的镍-雷尼催化剂表现出最高的BAF产率。在特定的反应条件下，酸处理的镍-雷尼催化剂的相对较高的Ni 0物种组成和较大的表面积极大地促进了BAF的形成。通过MALDI-MS分析证实了呋喃亚胺三聚体和四聚体等低聚物是DFF还原胺化反应的中间体。
The direct reductive amination of 2,5-diformylfuran (DFF) with ammonia to 2,5-bis(aminomethyl)furan (BAF) was demonstrated, for the first time, over the commercial type Nickel-Raney and acid treated Nickel-Raney catalysts. The effects of reaction parameters such as reaction medium, temperature and hydrogen pressure were described. The acid treated Nickel-Raney catalyst exhibited the highest BAF yield in the THF-water mixed reaction medium. The relatively higher Ni0 species composition and larger surface area of the acid treated Nickel-Raney catalyst with specific reaction conditions contributed greatly to the BAF formation. The oligomeric species, such as furanic imine trimers and tetramers confirmed by MALDI-MS analysis were presented as the intermediates of DFF reductive amination.