Catecholamine metabolism in the brains of ageing male mice.
Catecholamine metabolism in the brains of ageing male mice.
复制标题
衰老雄性小鼠大脑中的儿茶酚胺代谢。
DOI：
10.1016/0006-8993(73)90663-x
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发表时间：
1973
期刊：
影响因子：
2.9
通讯作者：
Caleb E. Finch
中科院分区：
文献类型：
--
作者：
Caleb E. Finch
在衰老的C57 B1/6 J雄性小鼠中观察到几种与年龄有关的儿茶酚胺代谢变化：（1）纹状体多巴胺水平降低，（2）四个脑区中l-[~ 3 H]酪氨酸和l-[~ 3 H]多巴向儿茶酚胺的转化减少，（3）下丘脑中总去甲肾上腺素和纹状体中总多巴胺的释放减慢。
Several age-related changes of catecholamine metabolism in senescent C57B1/6J male mice were observed: (1) reduced levels of striatal dopamine, (2) reduced conversion ofl-[3H]tyrosine andl-[3H]DOPA to catecholamines in 4 brain regions, and (3) slowed catabolism of total norepinephrine in the hypothalamus and of total dopamine in the striatum.