Temporal trends in sexual behaviours and their impacts on HIV incidence among South African women: 2002-2016.

Temporal trends in sexual behaviours and their impacts on HIV incidence among South African women: 2002-2016.
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DOI:
10.1080/09540121.2020.1789054
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发表时间:
2021-08
期刊:
影响因子:
1.7
通讯作者:
Ramjee G
Ramjee G
中科院分区:
医学4区
文献类型:
--
作者:
Wand H;Reddy T;Ramjee G

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South Africa has the highest number of HIV infected individuals in the world. The primary objective of the current study was to describe temporal changes in HIV incidence rates using the data from 9,948 women who enrolled in one of the six HIV prevention trials conducted in KwaZulu-Natal, South Africa (2002-2016). Characteristics of the study population were presented and compared across the four study periods: 2002-2004, 2005-2008, 2009-2011 and 2012-2016. Despite the significant progress in prevention programs, infection rates increased from 6.2 to 9.3 per 100 person-year over the 15 years. These rates were as high as 14 per 100 person-year among women younger than 20 years age. Being single/not cohabiting, using injectable contraceptives, having less than two children and diagnosed with STI(s) (at baseline) were consistently associated with increased risk of HIV infection in all four consecutive cohorts. These four factors were collectively associated with 71%, 75%, 80% and 88% of the HIV seroconversions in four study periods. As the research continues to find ways of controlling the spread of the infections, quantifying the temporal trends in risk factors and their population-level impacts on HIV infection may have significant implications. This information may assist in developing effective counselling and education programs by targeting the sexually active single women and delivering more realistic messages.
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