Risk of mortality and institutionalization in demented patients with delusions
Risk of mortality and institutionalization in demented patients with delusions
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DOI：
10.1177/089198879600900303
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发表时间：
1996-07-01
影响因子：
2.6
通讯作者：
Trabucchi, M
中科院分区：
文献类型：
--
作者：
Magni, E;Binetti, G;Trabucchi, M
妄想是痴呆症过程中的常见症状。然而，尽管它们具有临床相关性，但仍不清楚它们是否具有预后价值。这项纵向研究在基线时纳入了 99 名痴呆症 (AD) 和多发梗塞性痴呆 (MID) 患者，调查了基线时有或没有妄想症的患者从痴呆病房出院 2 年后的死亡和住院风险。结果表明，妄想的存在是未来住院治疗的重要预测因素（比值比 3.6，置信区间 1.3-9.6），即使年龄、教育水平以及认知和功能障碍严重程度等混杂因素得到统计控制。未发现对生存有显着影响。
Delusions are a common symptom during the course of dementia. Despite their clinical relevance, however, it is still unclear whether they are of prognostic value. This longitudinal study involving, at baseline, 99 demented Alzheimer disease (AD) and multi-infarct dementia (MID) patients, investigates the risk of mortality and institutionalization at 2 years after discharge from a dementia unit in patients with and without delusions at baseline. Results indicate that the presence of delusions is a significant predictor of future institutionalization (odds ratio 3.6, confidence interval 1.3-9.6), even when confounding factors such as age, educational level, and severity of cognitive and functional impairment are statistically controlled. No significant impact on survival was found.