Protein-protein interactions in the tetraspanin web
Protein-protein interactions in the tetraspanin web
复制标题
DOI：
10.1152/physiol.00015.2005
复制
发表时间：
2005-08-01
期刊：
影响因子：
8.4
通讯作者：
Shoham, T
中科院分区：
文献类型：
--
作者：
Levy, S;Shoham, T
Tetraspanins是进化上保守的膜蛋白，它们倾向于相互侧向结合，并在膜微区与许多伙伴蛋白动态聚集。因此，这个家族的成员参与细胞内和细胞间过程的协调，包括信号转导；细胞增殖、黏附和迁移；细胞融合；以及宿主与寄生虫的相互作用。
Tetraspanins are evolutionarily conserved membrane proteins that tend to associate laterally with one another and to cluster dynamically with numerous partner proteins in membrane microdomains. Consequently, members of this family are involved in the coordination of intracellular and intercellular processes, including signal transduction; cell proliferation, adhesion, and migration; cell fusion; and host-parasite interactions.