Ruthenium-catalyzed synthesis of quinolines from anilines and allylammonium chlorides in an aqueous medium via amine exchange reaction
Ruthenium-catalyzed synthesis of quinolines from anilines and allylammonium chlorides in an aqueous medium via amine exchange reaction
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DOI：
10.1016/s0040-4020(00)00694-3
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发表时间：
2000-09-22
期刊：
影响因子：
2.1
通讯作者：
Yoon, NS
中科院分区：
文献类型：
--
作者：
Cho, CS;Kim, JS;Yoon, NS
苯胺与烯丙基氯化铵在水介质（h2o -二氧六烷）中在催化量的RuCl2(PPh3)(3)和SnCl2存在下反应。2H(2)O得到相应的中高收率的喹啉。SnCl2的存在。2H(2)O是喹啉有效生成所必需的，提出了苯胺与烯丙基氯化铵交换胺生成亚胺的反应途径。(C) 2000 Elsevier Science Ltd.版权所有。
Anilines react with allylammonium chlorides in an aqueous medium (H2O-dioxane) in the presence of a catalytic amount of RuCl2(PPh3)(3) together with SnCl2. 2H(2)O to give the corresponding quinolines in moderate to good yields. The existence of SnCl2. 2H(2)O is necessary for the effective formation of quinolines, and a reaction pathway involving amine exchange reaction between anilines and allylammonium chlorides to form an imine is proposed for this catalytic process. (C) 2000 Elsevier Science Ltd. All rights reserved.