Examining the Link between Information Processing Speed and Executive Functioning in Multiple Sclerosis
Examining the Link between Information Processing Speed and Executive Functioning in Multiple Sclerosis
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DOI：
10.1093/arclin/acp007
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发表时间：
2009-02-01
影响因子：
2.6
通讯作者：
Isler, Robert B.
中科院分区：
文献类型：
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作者：
Drew, Margaret A.;Starkey, Nicola J.;Isler, Robert B.
多发性硬化症（MS）患者经常报告信息处理速度减慢（IPS），并且至少20%的人在执行功能的某些方面也受到损害。然而，这两个过程之间的关系还没有被研究过。对90名ms患者进行了Sternberg记忆扫描测试、处理速度指数（WAIS-III）、Delis Kaplan执行功能系统（D.KEFS）和工作记忆指数（WMS-III），他们在PSI上的表现明显低于标准得分，但记忆扫描速度没有明显的缺陷。Sternberg和PSI的初始反应速度与D.KEFS的表现关系更为密切，特别是在具有高认知需求的定时任务（切换任务）中。记忆扫描速度与工作记忆相关。本研究强化了多发性硬化症中IPS和工作记忆之间的联系，并支持IPS不是一个单一结构的观点。
Slowed information processing speed (IPS) is frequently reported in those with multiple sclerosis (MS), and at least 20% are compromised on some aspect of executive functioning also. However, any relationship between these two processes has not been examined. The Sternberg Memory Scanning Test, Processing Speed Index (WAIS-III), Delis Kaplan Executive Function System (D.KEFS), and Working Memory Index (WMS-III) were administered to 90 participants with MS. Their performance on the PSI was significantly below the normative scores but no deficits in memory scanning speed were evident. The initial response speed of the Sternberg and the PSI were more closely related to D.KEFS performance, particularly in timed tasks with a high cognitive demand (switching tasks). In contrast, memory scanning speed was related to working memory. This study reinforces the link between IPS and working memory in MS, and supports the suggestion that IPS is not a unitary construct.