Plasma exchanges in psoriasis

Plasma exchanges in psoriasis
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牛皮癣中的血浆交换

DOI:
10.1111/j.1365-2230.1984.tb00753.x
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发表时间:
1984
期刊:
Clincal and Experimental Dermatology
影响因子:
--
通讯作者:
J. Meynadier
J. Meynadier
中科院分区:
--
文献类型:
--
作者:
B. Guillot;J. Guilhou;D. Donadio;J. Meynadier

文献摘要

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5例难治性银屑病患者在4周内接受10次血浆置换治疗。在所有五次交易中,有三次交易后,情况有所改善。1例红皮病型银屑病患者在治疗后2天病情好转,但复发。4例患者的改善持续时间较短,复发发生在2 ~ 4周。循环免疫复合物在治疗前升高,每次交换后下降20%至70%。
Five patients with resistant psoriasis were treated with plasma exchanges performed ten times over a 4‐week period. Improvement was noted after three exchanges in all five. One patient with erythrodermic psoriasis became paler but relapsed 2 days after treatment. Improvement in four patients was of short duration with relapses occurring in 2 to 4 weeks. Circulating immune complexes were elevated before treatment and fell after each exchange by 20 to 70% of the former values.