Copper-catalyzed ligand-free amidation of aryl iodides and amino acid amides to synthesize C3-(Z)-1H-benzo[e][1,4]diazepin-2(3H)-ones
Copper-catalyzed ligand-free amidation of aryl iodides and amino acid amides to synthesize C3-(Z)-1H-benzo[e][1,4]diazepin-2(3H)-ones
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DOI：
10.1007/s11030-015-9603-5
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发表时间：
2015-06
影响因子：
3.8
通讯作者：
Xiao Hu;Yi Dong;Gang Liu
中科院分区：
文献类型：
--
作者：
Xiao Hu;Yi Dong;Gang Liu
AbstractAn effective synthetic method for C3-chiral 1,4-benzodiazepine-2-ones is described in this paper, reporting good yields and high enantioselectivity with a novel approach to an ipso-halo displacement-cyclization benzodiazepine route.Graphical abstract
