The Association Between Loneliness and Cognitive Impairment among Older Men and Women in China: A Nationwide Longitudinal Study
The Association Between Loneliness and Cognitive Impairment among Older Men and Women in China: A Nationwide Longitudinal Study
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中国老年男性和女性的孤独感与认知障碍之间的关系：一项全国范围的纵向研究
DOI：
10.3390/ijerph16162877
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发表时间：
2019-08-14
影响因子：
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通讯作者：
Fang, Ya
中科院分区：
文献类型：
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作者：
Zhou, Zi;Mao, Fanzhen;Fang, Ya
我们的目的是调查中国老年男性和女性的孤独感和认知障碍之间的关系。6898名年龄在65岁及以上的合格参与者的数据来自最近两波（2008/2009和2011/2012）中国健康长寿纵向调查。进行逻辑回归分析，以确定基线时的孤独感与随访时认知障碍风险之间的关联是否因性别而异，并对社会人口统计学变量、社会隔离、生活方式和健康状况进行调整。女性的基线孤独感和后续认知障碍的发生率均高于男性。在老年男性中，基线时的孤独症与随访时的认知功能障碍显著相关（OR = 1.30; 95% CI 1.01-1.69），即使在调整潜在混杂变量后也是如此;然而，在老年女性中未观察到类似的相关性（OR = 0.98; 95% CI 0.81-1.19）。采用多重插补处理缺失数据。虽然老年女性更经常报告孤独感，但孤独感对老年男性认知障碍的影响很大，但对老年女性没有影响。旨在减少孤独发生率的干预措施可能对减少中国老年男性的认知障碍特别有益。
We aimed to investigate the association between loneliness and cognitive impairment among older men and women in China. Data for 6898 eligible participants aged 65 years and older were derived from the latest two waves (2008/2009 and 2011/2012) of the Chinese Longitudinal Healthy Longevity Survey. A logistic regression analysis was performed to determine whether the association between loneliness at baseline and the risk of cognitive impairment at follow-up varied by sex, with adjustment for social-demographic variables, social isolation, lifestyles, and health status. The rates of baseline loneliness and follow-up cognitive impairment were both higher among women than men. Loneliness at baseline was significantly associated with cognitive impairment at follow-up among elderly men (OR = 1.30; 95% CI 1.01–1.69), even after adjusting for potential confounding variables; however, a similar association was not observed among elderly women (OR = 0.98; 95% CI 0.81–1.19). Multiple imputations were applied to address missing data. Although elderly women more frequently reported feelings of loneliness, the impact of loneliness on cognitive impairment was significant among elderly men but not elderly women. Interventions designed to decrease the incidence of loneliness may be particularly beneficial for the reduction of cognitive impairment among elderly Chinese men.