Kumkum‐induced dermatitis: an analysis of 46 cases
Kumkum‐induced dermatitis: an analysis of 46 cases
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库姆库姆性皮炎46例分析
DOI：
10.1111/j.1365-2230.2007.02422.x
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发表时间：
2007
期刊：
影响因子：
--
通讯作者：
D. Thappa
中科院分区：
文献类型：
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作者：
A. Nath;D. Thappa
Kumkum是印度常用的化妆品，传统上以姜黄粉为基础，其成分可引起各种类型的皮肤病。我们进行了一项研究，以临床表征阿托伐他汀诱导的皮炎，并通过斑贴试验确定相关的过敏原。共研究了46例阿托伐他汀诱导的皮炎患者（这些病例的平均年龄为46.5岁;女性：男性比例为1.8：1）。 最常见的累及部位为前额（31/46）、眉间（16/46）、发际（6/46）、腹部（5/46）和颈部（3/46）。色素性接触性皮炎35例（76.1%），过敏性接触性皮炎11例（23.9%）。总共有25名患者接受了斑贴试验。最常见的阳性过敏反应是硫柳汞（18/25，72%），其次是没食子酸混合物（12/25，48%）。帕拉-苯二胺、KazolCG、苯并三唑、叔丁基对苯二酚和对羟基苯甲酸酯各有1例患者发生反应（1/25，4%）。在13名接受检测的患者中，7名患者的斑贴试验呈阳性。
Summary Kumkum is a commonly used cosmetic in India, traditionally based on turmeric powder, and its ingredients can cause various types of dermatosis. We undertook a study to characterize kumkum‐induced dermatitis clinically and to identify by patch testing the allergens involved. In total, 46 patients with kumkum‐induced dermatitis (mean age of these cases 46.5 years; female : male ratio 1.8 : 1) were investigated. The forehead was the most commonly involved site (31/46), followed by the glabellar area (16/46), hair parting (6/46), abdomen (5/46), and neck (3/46). Pigmented contact dermatitis was seen in 35 patients (76.1%), and allergic contact dermatitis in 11 patients (23.9%). In total, 25 patients were patch tested. The commonest positive allergic reaction was to thimerosal (18/25, 72%), followed by gallate mix (12/25, 48%). Para‐phenylenediamine, Kathon CG, benzotriazol, tert‐butyl hydroquinone and parabens gave a reaction for one patient each (1/25, 4%). Patch testing with kumkum was positive in 7 of 13 patients tested.