A concentration-dependent switch in the bacterial response to temperature
A concentration-dependent switch in the bacterial response to temperature
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DOI：
10.1038/ncb1632
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发表时间：
2007-09-01
影响因子：
21.3
通讯作者：
Libchaber, Albert
中科院分区：
文献类型：
--
作者：
Salman, Hanna;Libchaber, Albert
我们观察到，细菌生长低于临界浓度，在分批模式的文化，游泳向温暖的地区时，受到温度梯度。超过这个浓度，它们就会游向更冷的区域。我们的发现表明分泌的细胞间信号甘氨酸通过Tsr受体的甲基化介导这种转换。在高细菌浓度下，通过Tar/Tsr表达比率的反转来加强开关。
We observed that bacteria grown below a critical concentration, in batch-mode cultures, swim towards warm regions when subjected to a temperature gradient. above that concentration, they swim towards colder regions. our findings indicate that the secreted intercellular signal, glycine, mediates this switch through methylation of Tsr receptors. at high bacterial concentration, the switch is reinforced by an inversion of the Tar/Tsr expression ratio.