Prevalence of Meniere's disease in general population of Southern Finland
Prevalence of Meniere's disease in general population of Southern Finland
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DOI：
10.1016/j.otohns.2005.06.015
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发表时间：
2005-11-01
影响因子：
3.4
通讯作者：
Pyykkö, I
中科院分区：
文献类型：
--
作者：
Havia, M;Kentala, E;Pyykkö, I
目的：研究梅尼埃病（MD）在芬兰南部的一般人群中的患病率。研究设计和设置：基于人口登记数据的前瞻性研究。一份调查问卷被发送到5000名随机选择的人年龄在12岁或以上的生活在赫尔辛基大学医院区。我们询问了接受者是否经历过与运动感、听力损失或耳鸣相关的眩晕。出于排除的目的，我们还询问了一般疾病，耳部感染，以前的头部和耳部创伤，噪音暴露，药物治疗以及烟草和酒精的使用。为了评估这项基于人群的研究的有效性，我们在报告眩晕的人群中随机选择了100人。他们在我们的前庭单位进行了临床检查。结果：有效率为63%。在最后的研究样本3116人，216人报告了眩晕，听力损失和耳鸣的三联征。通过使用最新的标准，听力和平衡的美国耳鼻咽喉头颈外科学会的委员会，我们能够确定16个明确的MD患者从总样本中，产生的患病率为5 - 13的10万人。在16例MD受试者中，9例患者已被诊断为MD，1例患者在临床检查期间被诊断。1709的100，000的患病率高峰出现在年龄组6 1至70 years.CONCLUSIONS：我们的人口为基础的估计MD患病率是远远高于以前的reports.EBM评级：B-3。(C)2005年美国耳鼻咽喉头颈外科基金会All rights reserved.
OBJECTIVE: To study the prevalence of Meneire's disease (MD) in the general population of Southern Finland.STUDY DESIGN AND SETTING: Prospective study based on population register data. A questionnaire was sent to 5000 randomly selected persons aged 12 years or more living in the Helsinki University Hospital area. We enquired about whether recipients had experienced vertigo associated with a moving sensation, hearing loss, or tinnitus. For exclusion purposes, we also asked about general illnesses, ear infections, former head and ear traumas, noise exposure, medication, and use of tobacco and alcohol. To assess the validity of the population-based study, we randomly selected a sample of 100 people among those reporting vertigo. They were clinically examined at our vestibular unit. The clinical examination was supplemented by audiologic and otoneurologic tests.RESULTS: The response rate was 63%. In the final study sample of 3 116 people, 2 16 reported the triad of vertigo, hearing loss, and tinnitus. By using the most recent criteria of the Committee on Hearing and Equilibrium of the American Academy of Otolaryngology-Head and Neck Surgery, we were able to identify 16 definite MD patients from the total sample, yielding a prevalence of 5 13 of 100,000 persons. Among the 16 MD subjects, 9 patients had already been diagnosed with MD and 1 patient was diagnosed during the clinical examination. A peak prevalence of 1709 of 100,000 was seen in the age group 6 1 to 70 years.CONCLUSIONS: Our population-based estimate of MD prevalence is much higher than in previous reports.EBM RATING: B-3.(C) 2005 American Academy of Otolaryngology-Head and Neck Surgery Foundation, Inc. All rights reserved.