Biomedical applications of holographic microspectroscopy [Invited]
Biomedical applications of holographic microspectroscopy [Invited]
复制标题
DOI：
10.1364/ao.53.00g111
复制
发表时间：
2014-09-20
期刊：
影响因子：
1.9
通讯作者：
Park, YongKeun
中科院分区：
文献类型：
--
作者：
Jung, JaeHwang;Kim, Kyoohyun;Park, YongKeun
特定分子的鉴定和定量对于研究细胞、组织和器官的病理生理学以及疾病的诊断和治疗至关重要。基于定量相位成像或光学相干断层扫描技术的全息显微光谱学的最新进展显示出对活细胞和组织中的特定分子（例如，血红蛋白质）。为了提供重要的洞察全息光谱技术在生物学研究和相关的实际应用中的潜在就业，我们回顾了全息显微光谱技术的原理，并强调最近的研究。(C)2014年美国光学学会
The identification and quantification of specific molecules are crucial for studying the pathophysiology of cells, tissues, and organs as well as diagnosis and treatment of diseases. Recent advances in holographic microspectroscopy, based on quantitative phase imaging or optical coherence tomography techniques, show promise for label-free noninvasive optical detection and quantification of specific molecules in living cells and tissues (e.g., hemoglobin protein). To provide important insight into the potential employment of holographic spectroscopy techniques in biological research and for related practical applications, we review the principles of holographic microspectroscopy techniques and highlight recent studies. (C) 2014 Optical Society of America