Measuring sedentary behaviors in patients with idiopathic pulmonary fibrosis using wrist-worn accelerometers
Measuring sedentary behaviors in patients with idiopathic pulmonary fibrosis using wrist-worn accelerometers
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DOI：
10.1111/crj.12589
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发表时间：
2018-02-01
影响因子：
1.7
通讯作者：
Wilson, Andrew
中科院分区：
文献类型：
--
作者：
Atkins, Christopher;Baxter, Mark;Wilson, Andrew
特发性肺纤维化（IPF）患者随着病情的加重，肺功能受限程度增加.久坐行为的时间增加与生活质量下降有关。由于个体之间的心肺限制可变，因此难以确定呼吸系统疾病患者的活动阈值。测量久坐不动的行为是不混淆这种限制，可能是一个更好的测量活动在呼吸道疾病patients with respiratory diseases.ObjectivesTo测量久坐不动的时间在IPF患者使用腕戴accelerometers.MethodsThirty-nine IPF患者戴着GENEActiv actiwatch连续7天。参与者进行了用力肺活量，一氧化碳弥散量和6分钟步行距离（6 MWD）的测量。在每天最活跃的5小时内记录的平均加速度强度（单位：毫克）为43.8毫克，久坐时间为每天551.7分钟。每日久坐时间与M5值中度相关（Pearson相关系数-0.366，P=.030）。只有M5值预测久坐时间。久坐时间在一周中没有变化。有一个趋势，随着久坐时间的增加，1年和2年的死亡率更高。ConclusionsWrist佩戴加速度计可靠地收集数据，耐受性良好。IPF患者长时间处于久坐状态。在所使用的标准临床测量中，6 MWD可预测日常活动，但不能预测久坐时间;没有临床测量可预测久坐时间。久坐时间增加可能与IPF患者结局较差相关。
IntroductionIdiopathic pulmonary fibrosis (IPF) patients suffer increasing functional limitation with disease worsening disease. Increasing time in sedentary behavior has been associated with poorer quality of life. Determining thresholds for activity in patients with respiratory disease is difficult due to variable cardiorespiratory limitations between individuals. Measuring sedentary behavior is not confounded by this limitation and may be a better measurement of activity in patients with respiratory disease.ObjectivesTo measure sedentary time in patients with IPF using wrist-worn accelerometers.MethodsThirty-nine IPF patients wore a GENEActiv actiwatch continually for 7 days. Participants underwent measurement of forced vital capacity, diffusion capacity of carbon monoxide and 6-min walk distance (6MWD).ResultsValid data was captured from 35 of 39 participants (89.7%). Mean acceleration intensity recorded in the most active 5 h of each day (in milli-g) were 43.8 milli-g and sedentary time was 551.7 min per day. Daily sedentary time correlated moderately with M5 values (Pearson correlation -0.366, P=.030). Only M5 values predicted sedentary time. No variability in sedentary time was seen by day of the week. There was a trend toward higher 1 and 2-year mortality with increasing sedentary time.ConclusionsWrist-worn accelerometers reliably collected data and were well tolerated. IPF patients spent long periods of time in sedentary behaviors. Of the standard clinical measures used, 6MWD predicted daily activity but not sedentary time; no clinical measures predicted sedentary time. Increased sedentary time may be associated with poorer outcomes in IPF patients.