Human Electrical Muscular Incapacitation and Effects on QTc Interval
Human Electrical Muscular Incapacitation and Effects on QTc Interval
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DOI：
10.1111/1556-4029.13490
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发表时间：
2017-11-01
影响因子：
1.6
通讯作者：
Peele, Mark E.
中科院分区：
文献类型：
--
作者：
Gibbons, John A.;Mojica, Andrew J.;Peele, Mark E.
人类电肌肉失能（HEMI）是用来制服好斗的人。心脏电活动的变化被认为是这些人中一小部分人死亡的原因。本研究旨在确定HEMI暴露后QTc间期是否发生变化。24名参与者在5秒HEMI暴露前和暴露后30分钟内进行EKG读数。所有受试者的EKG均由数据设盲的心脏电生理学家读取，并计算QT校正（QTc）间期。采用Bazett法计算QTc间期。QTc延长定义为>430 ms，用于识别QTc延长的阈值为30 ms。5名受试者发生QTc延长，6名受试者发生QTc延长。1例受试者发生QTc延长超过500 ms，这有发生多灶性室性心动过速的风险。这些结果表明，HEMI暴露可能会导致EKG变化，并有室性心动过速的风险。
Human Electrical Muscular Incapacitation (HEMI) is used to subdue combative individuals. Changes in cardiac electrical activity have been proposed as the cause of death in a small fraction of these individuals. The current study sought to determine whether changes in QTc interval occur after HEMI exposure. Twenty-four participants had EKG readings before a 5-second HEMI exposure and within 30 min after exposure. All subject EKGs were read by a data-blinded cardiac electrophysiologist who calculated a QT corrected (QTc) interval. QTc interval was calculated using Bazett method. QTc prolongation was defined as >430 ms and a threshold of 30 ms for identifying QTc lengthening. Five participants experienced QTc prolongation and six had QTc lengthening. One participant developed QTc prolongation exceeding 500 ms, which carries a risk of developing multifocal ventricular tachycardia. These results suggest that HEMI exposure may cause EKG changes with a risk of ventricular tachycardia.