Keratoprosthesis: an update
Keratoprosthesis: an update
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DOI：
10.1097/00055735-200108000-00007
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发表时间：
2001-08-01
影响因子：
3.7
通讯作者：
Dohlman, Claes H.
中科院分区：
文献类型：
--
作者：
Khan, Bilal;Dudenhoefer, Eric J.;Dohlman, Claes H.
多孔聚四氟乙烯和聚氨酯裙边材料，以及聚（2-羟乙基甲基丙烯酸酯）共聚物，在接近“生物可整合”的人造角膜目标方面显示出了希望。一种利用巩膜触觉的新型固定方法也被引入来增加稳定性。在玻璃体视网膜手术过程中，一种可以缝入位置的全硅酮装置已经成功地暂时使用。角膜假体（KPro）手术的预后取决于术前诊断：移植物失败-非瘢痕性疾病>眼瘢痕性类天疱疮>化学烧伤>史蒂文斯-约翰逊综合征。KPro手术后眼内炎的可能性遵循这一方案。致病菌往往呈革兰氏阳性。改良的玻璃体视网膜技术也得到了发展，可以成功地治疗后段并发症。角膜假体科学比前几年发展得更快。然而，在世界范围内，使用KPro来解决复杂的角膜失明仍然有限。作者对2000年1月1日至2001年4月1日的英文文献进行了综述，并描述了角膜假体设计、材料、医疗和手术管理领域的进展。(C) 2001 Lippincott Williams & Wilkins公司
Porous polytetrafluoroethylene and polyurethane skirt materials, as well as copolymers of poly (2-hydroxyethyl methacrylate), have shown promise in approaching the goal of a "biointegratable" keratoprosthesis. A novel fixation method that uses scleral haptics also has been introduced to increase stability. An all silicone device that can be sewn into position has been used successfully, temporarily, during vitreoretinal procedures. The prognosis of keratoprosthesis (KPro) procedures depends on the preoperative diagnosis: graft failure-noncicatrizing disease>ocular cicatricial pemphigoid>chemical burns>Stevens-Johnson syndrome. The likelihood of endophthalmitis after KPro surgery follows this scheme. Causative organisms tend to be gram-positive. Modified vitreoretinal techniques also have been developed, allowing successful treatment of posterior segment complications. The science of keratoprosthesis is advancing more rapidly than in previous years. However, use of KPro to address complicated corneal blindness worldwide remains limited. The authors conducted an English language literature review from January 1, 2000 to April 1, 2001 and describe advances of note in the field of keratoprosthesis design, materials, and medical and surgical management. (C) 2001 Lippincott Williams & Wilkins, Inc.