Atypical transverse myelitis due to cytomegalovirus in an immunocompetent patient

Atypical transverse myelitis due to cytomegalovirus in an immunocompetent patient
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DOI:
10.1007/s10072-005-0506-6
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发表时间:
2005-12-01
影响因子:
3.3
通讯作者:
Bussone, G
Bussone, G
中科院分区:
医学4区
文献类型:
--
作者:
Rigamonti, A;Usai, S;Bussone, G

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巨细胞病毒(CMV)相关的横肌萎缩症是罕见的免疫功能正常的患者。我们报告一位73岁的男性,没有证据表明免疫妥协,谁开发急性横肌。脑脊液细胞增多提示中枢神经系统炎症反应,脊髓MRI表现为T1呈低信号,T2呈高信号,C7与T2之间呈DP,但无增强。高CSF抗CMV IgG指数和正常CSF IgG指数表明血脑屏障完整,并支持免疫功能正常患者中CMV诱导的肌病的诊断。
Cytomegalovirus (CMV)-associated transverse myelitis is rare in immunocompetent patients. We report a 73-year-old man with no evidence of immune compromise, who developed acute transverse myelitis. Cerebrospinal fluid pleocytosis indicated central nervous system inflammation, and spinal MRI showed weak signal hypointensity in T1, hyperintensity in T2 and DP between C7 and T2, but no contrast enhancement. High CSF anti- CMV IgG index with normal CSF IgG index indicated intact blood-brain barrier, and supported the diagnosis of CMV-induced myelitis in an immunocompetent patient.