GENOME RNAS AND POLYPEPTIDES OF REOVIRUS SEROTYPES 1, 2, AND 3
GENOME RNAS AND POLYPEPTIDES OF REOVIRUS SEROTYPES 1, 2, AND 3
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DOI:
10.1128/jvi.22.3.726-733.1977
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发表时间:
1977-01-01
影响因子:
5.4
通讯作者:
FIELDS, BN
中科院分区:
文献类型:
--
作者:
RAMIG, RF;CROSS, RK;FIELDS, BN
The virus-specific double-stranded genome RNA and polypeptides present in virions and [mouse fibroblast L] cells infected with the 3 mammalian reovirus serotypes were examined by co-electrophoresis in several different polyacrylamide gel systems. The double-stranded RNA and polyptide species previously described for type 3 Dearing had corresponding species in the other serotypes examined. In each serotype several RNA and polypeptide species had different electrophoretic mobilities from the corresponding RNA or polypeptide species of type 3 Dearing. The combination of electrophoretic variants among the RNA and polypeptides of the reovirus serotypes gave electrophoretic markers in all 10 of the reovirus genes. The usefulness of these electrophoretic markers in mapping the reovirus genome is discussed.