What went where? - Impaired object-location learning in patients with right hippocampal lesions
What went where? - Impaired object-location learning in patients with right hippocampal lesions
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DOI：
10.1002/hipo.20043
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发表时间：
2005-01-01
期刊：
影响因子：
3.5
通讯作者：
Milner, B
中科院分区：
文献类型：
--
作者：
Crane, J;Milner, B
三项研究探讨了右内侧颞叶结构在物体位置记忆中的作用。在前两项研究中，对118名选择性杏仁核-海马体切除术或前颞叶切除术（侵入或大部分保留海马区）的患者和33名健康参与者进行了阵列学习测试。广泛的右侧海马病变组受损的即时和延迟回忆和学习的标准。在第三项研究中，对其中75名患者进行了磁共振成像（MRI），以测量各种内侧颞叶结构中残留组织的范围。研究发现，右侧海马体的剩余程度是阵列学习性能的最佳预测因素，强调了其在构建空间物体表示方面的关键作用。(c)2004 Wiley-Liss，Inc.
The role of the right medial temporal-lobe structures in memory for object location was investigated in three studies. in the first two studies, 118 patients with selective amygdalo-hippocampectomy or with anterior temporal lobectomy (either invading or largely sparing the hippocampal region) and 33 healthy participants were tested on array learning. Groups with extensive right hippocampal lesions were impaired on immediate and delayed recall and on learning to criterion. in the third study, magnetic resonance imaging (MRI) was used in 75 of these patients to measure the extent of tissue remaining in the various medial temporal-lobe structures. The extent of right hippocampus remaining was found to be the best predictor of array-learning performance, underlining its critical role in building a representation of objects in space. (c) 2004 Wiley-Liss, Inc.