PROTEOLYTIC AND MICROBIAL INACTIVATION OF ENTEROVIRUSES

PROTEOLYTIC AND MICROBIAL INACTIVATION OF ENTEROVIRUSES
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DOI:
10.1016/0043-1354(72)90032-2
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发表时间:
1972-01-01
期刊:
影响因子:
12.8
通讯作者:
HERRMANN, JE
HERRMANN, JE
中科院分区:
环境科学与生态学1区
文献类型:
--
作者:
CLIVER, DO;HERRMANN, JE

文献摘要

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一些肠道病毒对蛋白水解酶敏感。A-9型科萨基病毒似乎是一个极端的例子。在有限的调查中,它被蛋白水解细菌(特别是铜绿假单胞菌)灭活。这种失活可以从病毒颗粒的吸附或聚集中区分出来:细菌细胞吸收了病毒外壳蛋白的14 C标记,而不是病毒核酸的32 P。
Some enteroviruses are susceptible to proteolytic enzymes. Coxsackie virus type A-9 seems to be an extreme example of this. It was inactivated by proteolytic bacteria (notablyPseudomonas aeruginosa)in a limited survey. This inactivation could be distinguished from adsorption or aggregation of the virus particles:14C label from the virus coat protein, but not32P from the viral nucleic acid, was taken up by the bacterial cells.