Estimating Left Ventricular Filling Pressure by Echocardiography
Estimating Left Ventricular Filling Pressure by Echocardiography
复制标题
DOI：
10.1016/j.jacc.2017.01.058
复制
发表时间：
2017-04-18
影响因子：
24
通讯作者：
Nagueh, Sherif F.
中科院分区：
文献类型：
--
作者：
Andersen, Oyvind S.;Smiseth, Otto A.;Nagueh, Sherif F.
心力衰竭的诊断可能具有挑战性，因为症状相当非特异性。左心室充盈压升高可用于确诊，但心导管插入术通常不实用。因此，超声心动图指标被用作标记的充盈压。EQUITIVES本研究探讨了全面超声心动图的可行性和准确性，以确定患者左室充盈压升高。方法我们进行了一项多中心研究，450例患者的心脏疾病的广泛的心脏导管插入术。左心房容积指数，结合血流速度和组织多普勒速度，用于估计LV充盈压。结果平均左室射血分数（LVEF）为47%，209例患者LVEF
BACKGROUND The diagnosis of heart failure may be challenging because symptoms are rather nonspecific. Elevated left ventricular (LV) filling pressure may be used to confirm the diagnosis, but cardiac catheterization is often not practical. Echocardiographic indexes are therefore used as markers of filling pressure.OBJECTIVES This study investigated the feasibility and accuracy of comprehensive echocardiography in identifying patients with elevated LV filling pressure.METHODS We conducted a multicenter study of 450 patients with a wide spectrum of cardiac diseases referred for cardiac catheterization. Left atrial volume index, in combination with flow velocities and tissue Doppler velocities, was used to estimate LV filling pressure. Invasively measured pressure was used as the gold standard.RESULTS Mean left ventricular ejection fraction (LVEF) was 47%, with 209 patients having an LVEF