Palladium-catalyzed carbonylation/acyl migratory insertion sequence.
Palladium-catalyzed carbonylation/acyl migratory insertion sequence.
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DOI：
10.1002/anie.200906349
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发表时间：
2010-02
影响因子：
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通讯作者：
Zhenhua Zhang;Yiyang Liu;M. Gong;Xiaokun Zhao;Yan Zhang;J. Wang
中科院分区：
文献类型：
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作者：
Zhenhua Zhang;Yiyang Liu;M. Gong;Xiaokun Zhao;Yan Zhang;J. Wang
Migratory insertion is one of the fundamental processes in organopalladium chemistry. In particular, migratory insertion of a CO ligand and the formation of reactive acylpalladium intermediate is a powerful method for introducing a carbonyl functionality into organic molecules. The catalytic cycle involving such a key step has been developed into one of the most important tools to synthesize various carbonyl compounds. However, for a long time, the scope of migratory insertion processes of organopalladium has been limited to those involving carbon monoxide. In view of the similarity between a carbene and carbon monoxide, one may conceive palladium–carbene as another species which may undergo migratory insertion (Scheme 1). Indeed, the migra-
