Diffuse optical imaging using spatially and temporally modulated light
Diffuse optical imaging using spatially and temporally modulated light
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DOI：
10.1117/1.jbo.17.7.071311
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发表时间：
2012-07-01
影响因子：
3.5
通讯作者：
Tromberg, Bruce J.
中科院分区：
文献类型：
--
作者：
O'Sullivan, Thomas D.;Cerussi, Albert E.;Tromberg, Bruce J.
作者描述了扩散光学成像（DOI）技术的发展，特别是使用空间和时间调制来控制近红外光在厚组织中的传播。我们目前的理论和方法的DOI专注于基于模型的技术定量，在体内测量内源性组织的吸收和散射特性。我们特别强调时间和空间频域方法的标量光子密度波的共同概念框架。在介绍了这些方法的历史、理论基础和仪器之后，我们简要回顾了我们研究的临床和临床前应用，以及我们对DOI技术未来的展望。2012年，美国光电仪器工程师学会（SPIE）。[DOI：10.1117/1.JBO.17.7.071311]
The authors describe the development of diffuse optical imaging (DOI) technologies, specifically the use of spatial and temporal modulation to control near infrared light propagation in thick tissues. We present theory and methods of DOI focusing on model-based techniques for quantitative, in vivo measurements of endogenous tissue absorption and scattering properties. We specifically emphasize the common conceptual framework of the scalar photon density wave for both temporal and spatial frequency-domain approaches. After presenting the history, theoretical foundation, and instrumentation related to these methods, we provide a brief review of clinical and preclinical applications from our research as well as our outlook on the future of DOI technology. 2012 Society of Photo-Optical Instrumentation Engineers (SPIE). [DOI: 10.1117/1.JBO.17.7.071311]