Improving Stem Cell Therapeutics with Mechanobiology.
Improving Stem Cell Therapeutics with Mechanobiology.
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DOI：
10.1016/j.stem.2015.12.007
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发表时间：
2016-01-07
期刊：
影响因子：
23.9
通讯作者：
Mooney DJ
中科院分区：
文献类型：
--
作者：
Shin JW;Mooney DJ
近年来，已经清楚的是，机械信号在维持干细胞功能中起着不可或缺的作用。在这里，我们将讨论如何在干细胞生物学中整合物理方法和工程原理，包括培养系统，临床前模型和功能评估，可以改善再生医学的临床应用。
In recent years, it has become clear that mechanical cues play an integral role in maintaining stem cell functions. Here we discuss how integrating physical approaches and engineering principles in stem cell biology, including culture systems, preclinical models, and functional assessment, may improve clinical application in regenerative medicine.