The influence of age on the response of major depression to electroconvulsive therapy: a C.O.R.E. Report.
The influence of age on the response of major depression to electroconvulsive therapy: a C.O.R.E. Report.
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DOI：
10.1097/00019442-200111000-00006
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发表时间：
2001-09
期刊：
影响因子：
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通讯作者：
M. K. O'Connor;R. Knapp;M. Husain;T. Rummans;G. Petrides;Glenn E. Smith;M. Mueller;K. Snyder;H. Bernstein;A. Rush;M. Fink;Charles Kellner
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文献类型：
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作者：
M. K. O'Connor;R. Knapp;M. Husain;T. Rummans;G. Petrides;Glenn E. Smith;M. Mueller;K. Snyder;H. Bernstein;A. Rush;M. Fink;Charles Kellner
As part of a C.O.R.E., multi-site longitudinal study comparing continuation electroconvulsive therapy (ECT) vs. continuation pharmacotherapy, the authors determined the response of 253 patients with major depression to acute-phase, bilateral ECT by use of the 24-item Hamilton Rating Scale for Depression. Remission rates for three age-groups, > or =65 years; 46-64 years; and < or =45 years, were 90 percent, 89.8 percent, and 70 percent, respectively. Age, as a continuous variable, positively influenced response to treatment. Bilateral, dose-titrated ECT is a highly effective acute treatment for major depression, and older age confers a greater likelihood of achieving remission.
