Quantitative spectroscopy of superficial turbid media
Quantitative spectroscopy of superficial turbid media
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DOI：
10.1364/ol.30.003165
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发表时间：
2005-12-01
期刊：
影响因子：
3.6
通讯作者：
Durkin, AJ
中科院分区：
文献类型：
--
作者：
Tseng, SH;Hayakawa, C;Durkin, AJ
我们报道了一种新的漫射光谱探头设计，用于确定混浊样品的表面体积的光学性质。基于光纤的探针采用与感兴趣的样品接触放置的高散射层。该层在光子从准直光源进入样品之前扩散光子，并通过扩散近似为描述在表面介质中传输的光提供基础。我们比较了这种改进的两层扩散模型与Monte Carlo模拟的性能。一组实验表明，这种方法的可行性，在混浊组织幻影也提出。用这种方法推导出的光学性质与用基准方法确定光学性质的结果吻合得很好。这里调查的探针设计的平均询问深度估计小于1 mm。（c）2005年美国光学学会。
We report a novel diffuse optical spectroscopy probe design for determining optical properties of superficial volumes of turbid samples. The fiber-based probe employs a highly scattering layer placed in contact with the sample of interest. This layer diffuses photons from a collimated light source before they enter the sample and provides a basis for describing light transported in superficial media by the diffusion approximation. We compare the performance of this modified two-layer diffusion model with Monte Carlo simulations. A set of experiments that demonstrate the feasibility of this method in turbid tissue phantoms is also presented. Optical properties deduced by this approach are in good agreement with those derived by use of a benchmark method for determining optical properties. The average interrogation depth of the probe design investigated here is estimated to be less than 1 mm. (c) 2005 Optical Society of America.