The ''trouble'' with salivary testosterone
The ''trouble'' with salivary testosterone
复制标题
DOI：
10.1016/j.psyneuen.2004.02.005
复制
发表时间：
2004-11-01
影响因子：
3.7
通讯作者：
Schwartz, EB
中科院分区：
文献类型：
--
作者：
Granger, DA;Shirtcliff, EA;Schwartz, EB
在一系列的研究中，我们确定了几个具体的问题，可以限制整合唾液睾酮在生物社会研究的价值。唾液睾酮测量在样本采集过程中可能受到很大影响，易受血液（血浆）泄漏到唾液中引起的干扰效应的影响，并且在样本存档时对储存条件敏感。唾液睾酮水平和方差、血清-唾液相关性、唾液睾酮与年龄和青春期发育的关系以及唾液睾酮水平个体差异随时间的稳定性存在性别差异。这些发现在几个层次的分析研究，旨在测试睾酮行为关系的生物社会模型具有重要意义。建议提供指导调查人员围绕这些“麻烦”与唾液睾酮。(C)2004 Elsevier Ltd.保留所有权利。
In a series of studies, we identify several specific issues that can limit the value of integrating salivary testosterone in biosocial research. Salivary testosterone measurements can be substantially influenced during the process of sample collection, are susceptible to interference effects caused by the leakage of blood (plasma) into saliva, and are sensitive to storage conditions when samples have been archived. There are gender differences in salivary testosterone levels and variance, the serum-saliva association, the relationship of salivary testosterone to age and pubertal development, and the stability of individual differences in salivary testosterone levels over time. The findings have important implications at several levels of analysis for research that aims to test biosocial models of testosterone-behavior relationships. Recommendations are provided to steer investigators around these "troubles" with salivary testosterone. (C) 2004 Elsevier Ltd. All rights reserved.