Head circumference and long-term outcome in small-for-gestational age infants
Head circumference and long-term outcome in small-for-gestational age infants
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DOI：
10.1515/jpm.2008.042
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发表时间：
2008-07-01
影响因子：
2.4
通讯作者：
Hara, Toshiro
中科院分区：
文献类型：
--
作者：
Ochiai, Masayuki;Nakayama, Hideki;Hara, Toshiro
目的：评估出生体重低于第10个百分位数的小于胎龄（SGA）婴儿生长发育的危险因素。 患者和方法：1995年至1998年入住新生儿重症监护病房的SGA婴儿被纳入研究。 56例无染色体异常、遗传性疾病、TORCH感染、重大异常和/或多胎的SGA婴儿，根据出生时头围（HC）≥或<10（th）百分位数分为34例不对称和22例对称SGA婴儿。评估直到 6 岁时的身体生长情况，包括 HC、发育商数 (DQ) 和智商 (IQ) 分数。 结果：对称 SGA 婴儿的体重、身高和 HC 水平低于不对称 SGA 婴儿，但 3 岁时总 DQ 或 6 岁时 IQ 分数较低。 1 岁时 HC 低于第 10 个百分位的 21 名 SGA 婴儿（非追赶组）的 DQ 总分（平均 96 比 105）和 IQ 分数（82 比 102）低于 34 名没有的 SGA 婴儿（追赶组）。 结论：这些结果表明，SGA 婴儿的精神运动发育取决于 1 岁时的 HC而不是出生时就这样。
Objectives: To assess risk factors for the growth and development of small-for-gestational age (SGA) infants whose birth weight was less than the 10(th) percentile.Patients and methods: SGA infants who were admitted to the neonatal intensive care unit from 1995 to 1998 were enrolled in the study. Fifty-six SGA infants, having no chromosomal abnormalities, inherited diseases, TORCH infections, major anomaly and/or multiple birth, were divided into 34 asymmetrical and 22 symmetrical SGA infants by >= or < 10(th) percentile head circumference (HC) at birth. The physical growth including HC, and the developmental quotient (DQ) and intelligent quotient (IQ) scores were evaluated up to 6 years of age.Results: Symmetrical SGA infants had lower levels of weight, height and HC, but not of total DQ at 3 years or IQ scores at 6 years of age than asymmetrical SGA infants. The 21 SGA infants who had a HC less than the 10(th) percentile at 1 year of age (non-catch-up group) showed lower total DQ (mean 96 vs. 105) and IQ (82 vs. 102) scores than 34 SGA infants who had not (catch-up group).Conclusions: These results suggested that psychomotor development of SGA infants depended on the HC at 1 year of age rather than that at birth.