Resolution of postoperative ileus in humans.
Resolution of postoperative ileus in humans.
复制标题
人类术后肠梗阻的解决。
DOI：
10.1097/00000658-198605000-00019
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发表时间：
1986
影响因子：
9
通讯作者：
Sarna,SK
中科院分区：
文献类型：
--
作者：
Condon,RE;Frantzides,CT;Cowles,VE;Mahoney,JL;Schulte,WJ;Sarna,SK
在13例患者的升结肠和降结肠中放置双极电极。他们的手术规模从剖腹探查术到全胃切除术不等。手术的大小和长度与术后肠梗阻的持续时间没有正相关性。信号记录长达4小时，每天长达8天的手术后休息期间，在一些患者，硬膜外或肠外硫酸吗啡给药后。电控制活动（ECA）的功率谱分析表明，在较低（2-9 cpm）和较高（9-14 cpm）的范围内的主导频率。在术后恢复期，左右结肠的平均ECA频率相对稳定，但观察到多种优势ECA频率关系。右结肠的模态模式是随着恢复的进展，从高到低的范围内的优势频率的转变，而左结肠的模态模式是在较高的频率范围内的ECA的持续优势。电反应活动（ERA）最初仅由随机的、无组织的单次爆发组成，但在术后最初3天内逐渐变得更加复杂，出现更有组织的爆发和簇，其中一些在国内外传播非常缓慢（约5cm/min）。ERA恢复达到高潮，通常在术后第三或第四天，伴随着长时间连续ERA的恢复，其中一些以更高的速度（约80 cm/min）传播，仅在外向方向，并伴有排气或排便。
Bipolar electrodes were placed in the ascending and descending colon of 13 patients during laparotomy. The magnitude of their operations varied from exploratory laparotomy to total gastrectomy. The magnitude and length of the operations performed did not correlate positively with the duration of postoperative ileus. Signals were recorded for up to 4 hours daily for up to 8 days after operation during periods of rest and, in some patients, after administration of epidural or parenteral morphine sulfate. Power spectrum analyses of electrical control activity (ECA) showed dominant frequencies in both lower (2-9 cpm) and higher (9-14 cpm) ranges. During postoperative recovery, the mean ECA frequencies in right and left colon were relatively constant, but a variety of dominant ECA frequency relationships were observed. The modal pattern in the right colon was a shift in the dominant frequency from the higher to the lower range as recovery progressed, while the modal pattern in the left colon was persistent dominance of ECA in the higher frequency range. Electrical response activity (ERA) initially was comprised of only random, disorganized single bursts but became progressively more complex through the initial 3 postoperative days with the appearance of more organized bursts and clusters, some of which propagated very slowly (about 5 cm/min) both orad and aborad. ERA recovery culminated, typically on the third or fourth postoperative day, with the return of long bursts of continuous ERA, some of which propagated at a higher velocity (about 80 cm/min) and exclusively in the aborad direction and which were accompanied by passage of flatus or by defecation.