The Preterm Prediction Study: Failure of midtrimester cervical sialidase level elevation to predict subsequent spontaneous preterm birth
The Preterm Prediction Study: Failure of midtrimester cervical sialidase level elevation to predict subsequent spontaneous preterm birth
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DOI：
10.1016/s0002-9378(99)70609-5
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发表时间：
1999-05-01
影响因子：
9.8
通讯作者：
McNellis, D
中科院分区：
文献类型：
--
作者：
Andrews, WW;Tsao, J;McNellis, D
目的：我们的目标是确定中期宫颈液唾液唾液酸酶活性、细菌性阴道病和随后的自然早产之间的任何关系。研究设计：在这项嵌套式病例对照研究中，所有自然早产的患者(n=126)在1.43和2.23nmo.Ml(-1)。Min(-1)与自然早产相关。在病例组和对照组中，细菌性阴道病和唾液酸酶活性升高的组合频率相似(P大于或等于0.63，以任一截止值为准)。细菌性阴道病患者唾液酸酶活性显著高于非细菌性阴道病患者(1.35+/-1.87 vs0.03+/-0.14 nmol)。Ml(-1)。MIN(-1)、P
OBJECTIVE: Our objective was to determine any associations among midtrimester cervical fluid sialidase activity, bacterial vaginosis, and subsequent spontaneous preterm birth.STUDY DESIGN: In this nested case-control study all patients (n=126) with spontaneous preterm birth at 1.43 and >2.23 nmol . mL(-1) . min(-1), respectively) was associated with spontaneous preterm birth. The frequency of combinations of bacterial vaginosis and elevated sialidase activity was similar (P greater than or equal to.63 with either cutoff) in case patients and control subjects. Sialidase activity was significantly higher among women with bacterial vaginosis than among those without bacterial vaginosis (1.35 +/- 1.87 vs 0.03 +/- 0.14 nmol . mL(-1) . min(-1), P