Polycaprolactone-enabled sealing and carbon composite electrode integration into electrochemical microfluidics
Polycaprolactone-enabled sealing and carbon composite electrode integration into electrochemical microfluidics
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DOI：
10.1039/c9lc00417c
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发表时间：
2019-08-07
期刊：
影响因子：
6.1
通讯作者：
Henry, Charles S.
中科院分区：
文献类型：
--
作者：
Klunder, Kevin J.;Clark, Kaylee M.;Henry, Charles S.
将电化学与微流体相结合对于包括多路复用、自动化和高通量筛选在内的广泛应用是有吸引力的。电化学仪器还具有低成本的优点，并且可以实现高分析物灵敏度。对于许多电化学微流体应用，碳电极比贵金属更理想，因为它们耐污染，具有高活性和大的电化学溶剂窗口。目前，制造具有集成碳电极的电化学微流体装置仍然是一个挑战。在这里，提出了一种新的系统，用于将聚己内酯（PCL）和碳复合电极集成到微流体中。PCL：碳复合材料对广泛的分析物具有优异的电化学活性以及高电导率（类似于1000 S m（-1））。新系统利用激光切割机，使用PCL作为粘合层快速，简单地制造微流体。作为概念验证应用，对水包油和油包水滴进行电化学分析。克里思介导的醇氧化的小规模电化学有机合成也被证明。
Combining electrochemistry with microfluidics is attractive for a wide array of applications including multiplexing, automation, and high-throughput screening. Electrochemical instrumentation also has the advantage of being low-cost and can enable high analyte sensitivity. For many electrochemical microfluidic applications, carbon electrodes are more desirable than noble metals because they are resistant to fouling, have high activity, and large electrochemical solvent windows. At present, fabrication of electrochemical microfluidic devices bearing integrated carbon electrodes remains a challenge. Here, a new system for integrating polycaprolactone (PCL) and carbon composite electrodes into microfluidics is presented. The PCL : carbon composites have excellent electrochemical activity towards a wide range of analytes as well as high electrical conductivity (similar to 1000 S m(-1)). The new system utilizes a laser cutter for fast, simple fabrication of microfluidics using PCL as a bonding layer. As a proof-of-concept application, oil-in-water and water-in-oil droplets are electrochemically analysed. Small-scale electrochemical organic synthesis for TEMPO mediated alcohol oxidation is also demonstrated.