Pentaerythritol as the core of multivalent glycolipids: synthesis of a glycolipid with three SO3Lea ligands.
Pentaerythritol as the core of multivalent glycolipids: synthesis of a glycolipid with three SO3Lea ligands.
复制标题
季戊四醇作为多价糖脂的核心：具有三个 SO3Lea 配体的糖脂的合成。
DOI：
10.1021/ol0514202
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发表时间：
2005
期刊：
影响因子：
--
通讯作者：
Guo,Zhongwu
中科院分区：
文献类型：
--
作者：
Xue,Jie;Zhu,Junmin;Marchant,RogerE;Guo,Zhongwu
以季戊四醇为核心，合成了一种含有三个SO3配体的糖脂。将该糖脂用于制备稳定性与不含糖脂的双链葡聚糖脂质体相似的糖脂质体。易于制备的季戊四醇衍生物被证明是以糖脂和簇状糖脂的形式多价展示碳水化合物的有用支架。
A glycolipid containing three SO3Lealigands was synthesized with pentaerythritol as the core. The glycolipid was used to prepare glycoliposomes that showed stability similar to that of DSPC liposomes without glycolipid. The easily prepared derivatives of pentaerythritol proved to be useful scaffolds for multivalent displaying of carbohydrates in the form of glycolipids and clustered glycoliposomes.